Alex has successfully completed a B.Sc (Hons) majoring in medical microbiology and immunology in 2015 at UNSW, Sydney. He finished with first class honours and published his first research paper in 2016 summerising his work on Campylobacter concisus pathotypes in gastroenteritis. In the same year, Alex started his PhD with VISP moving his research to HCV. He now specialises in B cell analyses, specifically broad neutralising antibodies and their importance for vaccine development in HCV.
Apol ÁD; Sølund C; Vinten C; Underwood AP; Bukh J; Weis N, 2025, 'Cure of chronic hepatitis C virus infection after DAA treatment only partially restores the functional capacity of exhausted T cell subsets: a systematic review', Frontiers in Immunology, 16, http://dx.doi.org/10.3389/fimmu.2025.1546915
Journal articles | 2025
Dalegaard MI; Winckelmann A; Fahnøe U; Underwood AP; Pedersen AG; Bollerup S; Bukh J; Weis N, 2025, 'Higher Rates of Viral Evolution in Chronic Hepatitis B Patients Linked to Predicted T Cell Epitopes', Viruses, 17, http://dx.doi.org/10.3390/v17050684
Fahnøe U; Ronit A; Berg RMG; Jørgensen SE; Mogensen TH; Underwood AP; Scheel TKH; Bukh J; Plovsing RR, 2022, 'A Distinct Dexamethasone-Dependent Gene Expression Profile in the Lungs of COVID-19 Patients', Journal of Infectious Diseases, 226, pp. 2137 - 2141, http://dx.doi.org/10.1093/infdis/jiac218
Journal articles | 2022
Sølund C; Underwood AP; Fernandez-Antunez C; Bollerup S; Mikkelsen LS; Villadsen SL; Fahnøe U; Winckelmann AA; Feng S; Nørløv Vinten CA; Dalegaard MI; Vizgirda G; Sørensen AL; Ramirez S; Bukh J; Weis N, 2022, 'Analysis of Neutralization Titers against SARS-CoV-2 in Health-Care Workers Vaccinated with Prime-Boost mRNA–mRNA or Vector–mRNA COVID-19 Vaccines', Vaccines, 10, http://dx.doi.org/10.3390/vaccines10010075
Journal articles | 2021
Kalemera MD; Capella-Pujol J; Chumbe A; Underwood A; Bull RA; Schinkel J; Sliepen K; Grove J, 2021, 'Optimized cell systems for the investigation of hepatitis C virus E1E2 glycoproteins', Journal of General Virology, 102, http://dx.doi.org/10.1099/JGV.0.001512
Journal articles | 2021
Lassaunière R; Fonager J; Rasmussen M; Frische A; Polacek C; Rasmussen TB; Lohse L; Belsham GJ; Underwood A; Winckelmann AA; Bollerup S; Bukh J; Weis N; Sækmose SG; Aagaard B; Alfaro-Núñez A; Mølbak K; Bøtner A; Fomsgaard A, 2021, 'In vitro Characterization of Fitness and Convalescent Antibody Neutralization of SARS-CoV-2 Cluster 5 Variant Emerging in Mink at Danish Farms', Frontiers in Microbiology, 12, http://dx.doi.org/10.3389/fmicb.2021.698944
Journal articles | 2021
Ramirez S; Fernandez-Antunez C; Galli A; Underwood A; Pham LV; Ryberg LA; Feng S; Pedersen MS; Mikkelsen LS; Belouzard S; Dubuisson J; Sølund C; Weis N; Gottwein JM; Fahnøe U; Bukh J, 2021, 'Overcoming culture restriction for SARS-CoV-2 in human cells facilitates the screening of compounds inhibiting viral replication', Antimicrobial Agents and Chemotherapy, 65, http://dx.doi.org/10.1128/AAC.00097-21
Journal articles | 2021
Underwood AP; Sølund C; Fernandez-Antunez C; Villadsen SL; Winckelmann AA; Bollerup S; Mikkelsen LS; Sørensen AL; Feng S; Fahnøe U; Lassauniere R; Fomsgaard A; Ramirez S; Weis N; Bukh J, 2021, 'Neutralisation titres against SARS-CoV-2 are sustained 6 months after onset of symptoms in individuals with mild COVID-19', Ebiomedicine, 71, http://dx.doi.org/10.1016/j.ebiom.2021.103519
Mina M; Underwood A; Eltahla A; Wu BR; Walker MR; Bull RA; Lloyd AR, 2020, 'Anti-envelope antibody responses in highly exposed seronegative individuals may be associated with protection from HCV infection', Journal of Viral Hepatitis, 27, pp. 1012 - 1021, http://dx.doi.org/10.1111/jvh.13339
Journal articles | 2019
Keck ZY; Pierce BG; Lau P; Lu J; Wang Y; Underwood A; Bull RA; Prentoe J; Velázquez-Moctezuma R; Walker MR; Luciani F; Guest JD; Fauvelle C; Baumert TF; Bukh J; Lloyd AR; Foung SKH, 2019, 'Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis c virus infections uncover molecular determinants for E2 targeting and vaccine design', Plos Pathogens, 15, pp. e1007772, http://dx.doi.org/10.1371/journal.ppat.1007772
Journal articles | 2019
Masavuli MG; Wijesundara DK; Underwood A; Christiansen D; Earnest-Silveira L; Bull R; Torresi J; Gowans EJ; Grubor-Bauk B, 2019, 'A hepatitis C virus DNA vaccine encoding a secreted, oligomerized form of envelope proteins is highly immunogenic and elicits neutralizing antibodies in vaccinated mice', Frontiers in Immunology, 10, http://dx.doi.org/10.3389/fimmu.2019.01145
Journal articles | 2019
Walker MR; Leung P; Eltahla AA; Underwood A; Abayasingam A; Brasher NA; Li H; Wu BR; Maher L; Luciani F; Lloyd AR; Bull RA, 2019, 'Clearance of hepatitis C virus is associated with early and potent but narrowly-directed, Envelope-specific antibodies', Scientific Reports, 9, pp. 13300, http://dx.doi.org/10.1038/s41598-019-49454-w
Journal articles | 2019
Wu BR; Eltahla AA; Keoshkerian E; Walker MR; Underwood A; Brasher NA; Agapiou D; Lloyd AR; Bull RA, 2019, 'A method for detecting hepatitis C envelope specific memory B cells from multiple genotypes using cocktail E2 tetramers', Journal of Immunological Methods, 472, pp. 65 - 74, http://dx.doi.org/10.1016/j.jim.2019.06.016
Journal articles | 2018
Castaño-Rodríguez N; Underwood AP; Merif J; Riordan SM; Rawlinson WD; Mitchell HM; Kaakoush NO, 2018, 'Gut microbiome analysis identifies potential etiological factors in acute gastroenteritis', Infection and Immunity, 86, pp. 10.1128/iai.00060 - 10.1128/iai.00018, http://dx.doi.org/10.1128/IAI.00060-18
Journal articles | 2018
Underwood AP; Walker MR; Brasher NA; Eltahla AA; Maher L; Luciani F; Lloyd AR; Bull RA, 2018, 'Understanding the determinants of BnAb induction in acute HCV infection', Viruses, 10, pp. 659, http://dx.doi.org/10.3390/v10110659
Journal articles | 2016
Underwood AP; Kaakoush NO; Sodhi N; Merif J; Lee WS; Riordan SM; Rawlinson WD; Mitchell HM, 2016, 'Campylobacter concisus pathotypes are present at significant levels in patients with gastroenteritis', Journal of Medical Microbiology, 65, pp. 219 - 226, http://dx.doi.org/10.1099/jmm.0.000216
Preprints | 2022
Fahnøe U; Ronit A; Berg RMG; Jørgensen SE; Mogensen TH; Underwood AP; Scheel TKH; Bukh J; Plovsing RR, 2022, A unique dexamethasone-dependent gene expression profile in the lungs of COVID-19 patients, http://dx.doi.org/10.1101/2022.01.12.22269048
Preprints | 2020
Kalemera M; Cappella-Pujol J; Chumbe A; Underwood A; Bull R; Schinkel J; Sliepen K; Grove J, 2020, Optimised cell systems for the investigation of hepatitis C virus E1E2 glycoproteins, http://dx.doi.org/10.1101/2020.06.18.159442
